Alzheimer’s disease (AD) is a common form of dementia
that leads to impairment of memory and difficulties in judgment, discernment, logic
and planning. Symptoms of this disease build up gradually and become worse in
due course. Strikingly, they may still turn out to be brutal enough to hamper
daily errands of the patient. The disease brings about obliteration of
connections linking nerve cells over time and ultimately breakdown of brain
tissues. Pearl posits that the AD was named after Alois Alzheimer, the doctor
who initially explained it (32). Currently, the disease has no recognized cure
although treatments for symptoms help slow the aggravation of its symptoms.
Causes
Habitually, older people get the disease but it ought to
be noted that AD is not an ordinary facet of aging. It is a consequence of two
major forms of nerve damage. The primary kind of damage is neurofibrillary
tangles where nerve cells get ‘tangles’. The second type of nerve damage
involves build up of protein deposits called ‘senile plaques’ (Brill 15). These
types of nerve damage bring about death of nerve cells over time and ultimately
breakdown of brain tissues.
Alzheimer’s disease is also caused by deficiency of
various essential chemicals in the brain. This results in failure of efficient
transmission of signals around the brain which is a core function of these
chemical messengers. For that reason, a dearth of chemical messengers causes
symptomatic effects of Alzheimer’s disease.
According to Lee et al, age-related transformations of
the brain explain why AD mainly strikes old people. Various scientists have
explained that these changes such as inflammation, degeneration of various
brain elements and mitochondrial dysfunction harms the neurons within the
brain. This consequently causes Alzheimer’s damage (1539).
To sum up, Alzheimer’s disease deprives people of their
memory. Though scientists aren’t sure of its direct cause, they have attributed
its symptoms to the abovementioned factors. Noticeably, these factors are
accelerated by risk factors such as age, genetics, family history, heart
health, way of life and sex.
Works
Cited
Brill,
Marlene T. Alzheimer's Disease. New York: Benchmark Books, 2005. Print.
Lee,
Young-Jung, et al. "Inflammation
and Alzheimer’s disease." Archives
of pharmacal research 33.10 (2010): 1539-1556.
Perl, Daniel P. "Neuropathology
of Alzheimer's disease." Mount Sinai Journal of Medicine: A Journal of
Translational and Personalized Medicine 77.1 (2010): 32-42.
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